First off, not all of us consider 350 low water, and I much prefer it for swinging flies to the 1000+ I've had to contend with for the last few years. I think 2bob and I have both indicated, as did the fish that made it upriver, that 350 is more than adequate for them to run and for many to escape the "gauntlet" in town. And 350 is more than adequate to dissolve adequate oxygen, concentration of which has nothing to do with flow unless the fish are crammed together like in a hatchery, but is much more related to temperature and turbulence. I have not heard anything about gill lice in Lake Ontario, but I recalls seeing a lot of discussion about this happening in Erie tribs last year, and anything that happens up in LE, eventually gets down to us in Lake Ontario. Somebody probably brought them here in a bait bucket! But gill lice have been a normal thing for west coast steel. But I'll send out some questions when I get to the email lists at work.
I'm always using the 8 anymore (since the 6 got stolen), and 2x is pretty much standard as well. I'll see how this holds up in winter mode if it stays up above freezing, other wise its 12 lb mainline with a 8lb leader.
L13